Neonatal hypothermia is a condition which is faced by both general practitioners, as well as pediatricians, in routine practice. Neonatal hypothermia has been recognized by the World Health Organization (WHO) as a factor contributing to the morbidity and mortality risk of newborns. Neonatal hypothermia may occur because of exposure to a cold environment, contact with a cold object/surface, if the baby is wet or not clothed properly, neonatal sepsis, intracranial hemorrhage and other reasons. It may result in adverse consequences. It can be easily prevented by giving skin to skin contact and maintaining the warm chain. Here, a practical, clinical approach with preventive measures is discussed.