Brain Oriented Resuscitation in the First Hour- Strategies
Cerebral Ischemia is defined as diminution of cerebral blood flow (CBF) to a critical threshold that propagates brain damage involving the entire brain or a selective region. Global cerebral ischemia occurs commonly in patients who have a variety of clinical conditions including cardiac arrest (CA), shock, and asphyxia. In addition to injury to other organs from systemic hypoperfusion, neurologic sequelae from brain injury are varied and constitute a spectrum that includes coma, seizures, ischemic stroke, delirium, and neurocognitive impairment.
Post-resuscitation neurologic management: Meaningful neurologic survival represents the most clinically relevant outcome measure for cardiopulmonary resuscitation (CPR). Unfortunately, survival with neurologic sequelae is common for both adult and pediatric victims of cardiac arrest.