Seizures are a common occurrence in both term and preterm neonates. Neonatal convulsion is a paroxysmal disturbance in the neurological function of neurons. They require immediate evaluation because the underlying condition might insult the developing and vulnerable neurons of neonates. Seizures are easily recognizable and require quick treatment. However, sometimes they can be missed. This review article focuses on a brief introduction, the aetiology and various types of seizures, and the clinical approach, different diagnostic methods and management of seizures due to the underlying condition. Hypoxic-ischemic encephalopathy is the most common cause of neonatal seizure. Other causes are metabolic, infectious (meningitis), intracranial haemorrhage, developmental defects, and other miscellaneous causes. Management depends on underlying causes.