A One-year Study of Colorectal Cancer in a Tertiary Care Hospital

A One-year Study of Colorectal Cancer in a Tertiary Care Hospital

Malignant neoplasms are more common than benign lesions in the colorectum. Patients above 50 years are affected more commonly, and the maximum incidence of both benign and malignant lesions is seen in the 6th decade. In this study, it was also seen that females were more affected (marginally) as compared to males in the present study. Rectum is the most frequent site of occurrence of neoplasms. Adenocarcinoma is the commonest tumour of colorectum. The prevalence of CRCs in age, site, and histopathological type was comparable to other studies done in India and abroad. The commonest polypoidal lesion is adenomatous polyp followed by hyperplastic polyp.

An increasing incidence of colorectal malignancies has been observed in patients less than 50 years of age. Family history, consumption of alcohol and red meat, obesity, and cigarette smoking are risk factors associated with malignant neoplasms in this area. Thus, any patient having a change in bowel habits, iron deficiency anaemia, abdominal pain, blood or mucus in stool, should be examined (digital rectal examination) and investigated by proctosigmoidoscopy/ colonoscopy and other radiological tests for early diagnosis and management of colorectal carcinoma.

Uncommon and Unexpected Gallbladder Lesions

Uncommon and Unexpected Gallbladder Lesions

Gallbladder carcinoma is a rare malignancy, usually seen in the sixth to seventh decade of life, with a strong female predominance. The prevalence varies in different parts of the world. In India, the Indian Council of Medical Research has found an incidence of 4.5/lakh population in males, and 10.1/lakh population in females in North India and 1.2/lakh population in South India respectively. Carcinoma often presents with signs and symptoms of cholecystitis and may not be suspected clinically and sometimes even in gross examination. Hence, it is essential that all gallbladders that are removed are thoroughly sampled. Associated cholelithiasis may be seen in 80% of cases. We had one case which presented as cholecystitis, and malignancy was not suspected clinically. These tumours are located in the body or fundus in 90% of the cases. On gross appearance they may be seen as nodular or polypoid masses, as a thickening of the wall or as a diffusely infiltrating tumour.