Acupuncture

Acupuncture

Numerous claims have been made by the Acupuncturists that ailments like Arthritis, Ulcers, Lumbago, Paralysis due to Polio, or Stroke, Bronchial Asthma, Mental retardation, have yielded to an implant of a set of needles in the correct acupuncture points for varying periods of time. According to some physicians Migraine, Spondylo Arthritis, Piles, Hyper acidity, Peptic ulcers, alcohol addiction, drug addiction, smoking, and many other ailments have responded considerably to acupuncture.

Ayurveda – The science of Life

Ayurveda – The science of Life

Ayurveda is the ancient Indian medical science, the origin of which can be traced back to the Vedas-ancient books of knowledge containing various subjects.
Ayurveda has its history dating dack to 5000 years. Some of the literature, texts for eg. Kashyap samhita (on paediatrics) was destroyed during foreign invasions. The 3 main texts in Ayurveda include – Charak Samhita (internal medicine), Sushruta samhita (mainly surgery), Ashtang Sangraha.
The texts in their original form are written in the form of shlokas or verses in Sanskrit.

Potpourri of Rare Central Nervous System Tumors

Potpourri of Rare Central Nervous System Tumors

Oncologic surgical neuropathology is a dynamic field. The unparalleled complexity of the central nervous system (CNS) is mirrored by the ever-increasing diversity of recognized neoplastic entities that can afflict the organ. In many instances, the emergence of ‘‘new’’ entities are a reflection of our increasing ability to sub divide large categories of tumors into more refined, clinically and biologically meaningful, subtypes for purposes of patient prognosis and/ or treatment stratification.

Hypothyroidism and Diabetes Mellitus

Hypothyroidism and Diabetes Mellitus

Diabetes mellitus (DM) is the second most commonly occurring endocrine disorder with thyroid dysfunction. Patients with Type 1 Diabetes Mellitus or insulin dependent diabetes mellitus may have coexisting thyroid disease, thyroid specific antibodies, and/or evidence of polyglandular endocrinopathy (such as anti-islet cell antibodies, anti-insulin antibodies and antibodies to other endocrine organs).

Modern approaches to designing novel CD80 inhibitors that mimic biological effects of Abatacept

Modern approaches to designing novel CD80 inhibitors that mimic biological effects of Abatacept

T-cell activation plays a critical role in driving normal and pathogenic immune responses. The interaction between cell surface co-stimulatory molecules on antigen-presenting cells and the T cells is essential for modulating cell to cell communication and the immune response. Two structurally and functionally well characterized T cell surface co-stimulatory molecules are CD28 and CD152 (CTLA-4), both of which bind the ligands CD80 and CD86, on the antigen-presenting cells (APCs). Disruption of CD80-CD28 interactions (which is involved in T cell activation) is an established target for rheumatoid arthritis (RA), transplant rejection, non-Hodgkin’s lymphoma (NHL) and other applications where suppression of T cell activity is desirable.